Full Material List

genistein

5,7-dihydroxy-3-(4-hydroxyphenyl)chromen-4-one


Material Info

FEMA N/A
CAS 446-72-0
EINECS 207-174-9
JECFA Food Flavoring N/A
CoE Number N/A
Organoleptic Notes
  • Odor and/or flavor descriptions from others (if found).
Odor N/A
Flavor N/A
Material Notes an isoflavonoid derived from soy products. it inhibits protein-tyrosine kinase and topoisomerase-ii (dna topoisomerases, type ii); activity and is used as an antineoplastic and antitumor agent. experimentally, it has been shown to induce g2 phase arrest in human and murine cell lines and inhibits protein-tyrosine kinase. Genistein is a phenolic compound belonging to the isoflavonoid group. Isoflavonoids are found mainly in soybean. Genistein and daidzein (an other isoflavonoid) represent the major phytochemicals found in this plant. Health benefits (e.g. reduced risk for certain cancers and diseases of old age) associated to soya products consumption have been observed in East Asian populations and several epidemiological studies. This association has been linked to the action of isoflavonoids. With a chemical structure similar to the hormone 17-b-estradiol, soy isoflavones are able to interact with the estrogen receptor. They also possess numerous biological activities. (PMID: 15540649)

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