| FEMA | N/A |
| CAS | 65277-42-1 |
| EINECS | 265-667-4 |
| JECFA Food Flavoring | N/A |
| CoE Number | N/A |
| Organoleptic Notes |
|
| Odor | N/A |
| Flavor | N/A |
| Material Notes | broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients. Ketoconazole (pronounced /ËŒkiËtoʊˈkoÊŠnÉ™zoÊŠl/) is a synthetic antifungal drug used to prevent and treat skin and fungal infections, especially in immunocompromised patients such as those with AIDS. Ketoconazole is sold commercially as an anti-dandruff shampoo. Ketoconazole is very lipophilic, which leads to accumulation in fatty tissues. The less toxic and more effective triazole compounds fluconazole and itraconazole have largely replaced ketoconazole for internal use. Ketoconazole is best absorbed at highly acidic levels, so antacids or other causes of decreased stomach acid levels will lower the drug's absorption when taken orally. -Wikipedia [HMDB] |