FEMA | N/A |
CAS | 154-93-8 |
EINECS | 205-838-2 |
JECFA Food Flavoring | N/A |
CoE Number | N/A |
Organoleptic Notes |
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Odor | N/A |
Flavor | N/A |
Material Notes | Isol. from the common clam Mercenaria mercenaria and from Mercenaria campechiensis Carmustine is one of the nitrosoureas indicated as palliative therapy as a single agent or in established combination therapy with other approved chemotherapeutic agents in treatment of brain tumors, multiple myeloma, Hodgkin's disease, and non-Hodgkin's lymphomas. Although it is generally agreed that carmustine alkylates DNA and RNA, it is not cross resistant with other alkylators. As with other nitrosoureas, it may also inhibit several key enzymatic processes by carbamoylation of amino acids in proteins. |