para-methyl anisole

Full Material List

1-methoxy-4-methylbenzene

Identifiers

CAS (Single)	104-93-8
FEMA	2681
EINECS	203-253-7
Synonyms	anisole, p-methyl- benzene, 1-methoxy-4-methyl- p- cresol methyl ether para- cresol methyl ether p- cresyl methyl ether para- cresyl methyl ether p- cresyl methyl ether ( p â€“ cresol ) p- cresyl methyl ether FCC cresyl methyl ether para cresyl methyl ether para FCC 1- methoxy-4-methyl benzene 1- methoxy-4-methyl-benzene 1- methoxy-4-methylbenzene 4- methoxytoluene p- methoxytoluene para- methoxytoluene methyl 4-methyl phenyl ether methyl 4-methylphenyl ether 4- methyl anisole p- methyl anisole para- methyl anisole para- methyl cresol methyl p-cresol o- methyl p-cresol methyl p-cresyl ether methyl p-methylphenyl ether methyl p-tolyl ether methyl para cresol ortho- methyl para-cresol methyl para-cresyl ether methyl para-methyl phenyl ether methyl para-tolyl ether 4- methyl phenol methyl ether 4- methyl-1-methoxybenzene 1- methyl-4-methoxybenzene methyl-para-cresol 4- methylanisole p- methylanisole para- methylanisole 4- methylcresol p- methylcresol 4- methylphenol methyl ether toluene, 4-methoxy- p- tolyl methyl ether para- tolyl methyl ether
JECFA Food Flavoring	1243
JECFA Food Additive	N/A
DG SANTE Food Flavourings	04.015 1-methoxy-4-methylbenzene
DG SANTE Food Contact Materials	N/A
FDA UNII	10FAI0OR9W
CoE Number	188
XlogP3-AA	2.70 (est)
Molecular Weight	122.1669
Molecular Formula	C8 H10 O

Properties

Food Chemicals Codex Listed	Yes
Appearance	colorless clear liquid (est)
Assay	99.00 to 100.00
Specific Gravity	0.99600 to 1.00400 @ 25.00 °C.
Lbs/Gal (est)	8.288 to 8.354
Refractive Index	1.51000 to 1.51300 @ 20.00 Â°C.
Melting Point	-32.00 Â°C. @ 760.00 mm Hg
Boiling Point	175.50 Â°C. @ 760.00 mm Hg
Flash Point	128.00 Â°F. TCC ( 53.33 Â°C. )
Acid Value	N/A
Vapor Pressure	2.029000 mmHg @ 25.00 Â°C. (est)
Vapor Density	N/A
logP (o/w)	2.66
Soluble In	alcohol dipropylene glycol fixed oils water, 527.1 mg/L @ 25 °C (est) glycerin propylene glycol water non-discoloring in most media
Occurrence	cananga cananga odorata oil java @ 2.14% cananga oil china @ 2.05% champaca concrete @ trace% cheese cheese gorgonzola cheese croton flavens l. (welensali) leaf oil curacao @ trace% hyacinthus orientalis absolute @ 0.01-0.02% lavender oil spike spain @ 0.009% tomato ylang ylang ylang ylang oil @ 0.34% ylang ylang oil CO2 extract @ 2.00% ylang ylang oil I (cananga odorata hook. f. and thomas.) @ 5.75% ylang ylang oil II (cananga odorata hook. f. and thomas.) @ 1.19% ylang ylang oil III @ 0.39%

Organoleptic

Organoleptic Notes	1. Odor Type: naphthyl Odor Strength:high ,recommend smelling in a 1.00 % solution or less Substantivity:8 hour(s) at 100.00 % naphthyl narcissus ylang powdery nutty Odor Description:at 1.00 % in dipropylene glycol. naphthyl cresol ylang powdery nuttyLuebke, William tgsc, (1996) Odor sample from: Ungerer & Company, Inc. naphthyl phenolic camphoreous minty powdery nutty Odor Description:Naphthyl, phenolic, camphoraceous, minty, powdery and nuttyMosciano, Gerard P&F 15, No. 3, 51, (1990)
Odor	naphthyl naphthyl, narcissus, ylang, powdery, nutty, phenolic, camphoreous, minty
Flavor	naphthyl naphthyl, phenolic, camphoreous, cooling, woody,

AInsights BETA

FlavScents AInsights Entry for para-Methyl Anisole (CAS: 104-93-8)

1. Identity & Chemical Information

Common Name(s): para-Methyl Anisole, p-Methylanisole
IUPAC Name: 1-Methoxy-4-methylbenzene
CAS Number: 104-93-8
FEMA Number: Data not found
Other Identifiers: FL Number: Data not found; CoE Number: Data not found; IFRA Reference: Data not found
Molecular Formula: C8H10O
Molecular Weight: 122.16 g/mol

para-Methyl anisole is characterized by a methoxy group attached to a benzene ring, which contributes to its aromatic properties. The presence of the methoxy group is crucial for its odor profile, providing a sweet, anisic scent that is often associated with licorice or fennel-like aromas.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

para-Methyl anisole is known for its sweet, anisic odor with a character reminiscent of licorice and fennel. It is often described as having a moderate intensity and good diffusion properties, making it a valuable component in both flavor and fragrance formulations. The taste and odor thresholds for para-methyl anisole are not clearly reported in the literature, but its sensory role is typically as an impact note or a modifier, enhancing the overall profile of a formulation.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

para-Methyl anisole is naturally found in several essential oils, including anise and fennel oils. It can also be formed through the methylation of anisole, a process that can occur naturally or be synthetically replicated. Its presence in natural sources makes it relevant for "natural flavor" or "natural fragrance" designations, depending on the extraction and processing methods used.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

para-Methyl anisole is used in various flavor categories, particularly in confectionery, beverages, and bakery products, where it imparts a sweet, licorice-like note. Its functional role in flavor systems is often as a modifier or an impact note, enhancing the sweetness and complexity of the flavor profile. Typical use levels in finished food or beverage products range from 1 to 10 ppm, with variations depending on the specific application and desired intensity. It is generally stable under typical processing conditions, but care should be taken to avoid excessive heat and oxidation, which can degrade its aromatic properties.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

In the fragrance industry, para-methyl anisole is utilized in various fragrance families, including floral, oriental, and gourmand. It serves as a modifier or an impact note, contributing a sweet, anisic aroma that enhances the overall fragrance composition. Typical concentration ranges in fragrance formulations are from trace amounts up to 1%, depending on the desired effect and product type. Its volatility allows it to contribute primarily to the top and middle notes of a fragrance.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

United States: para-Methyl anisole is not explicitly listed as GRAS by FEMA, but it is used in compliance with general safety standards.
European Union: It is used under the framework of Regulation (EC) No 1334/2008, but specific FL number status is not clearly reported.
United Kingdom: Post-Brexit, the regulatory alignment with the EU remains, but specific divergences are not documented.
Asia: In Japan and China, para-methyl anisole is used in flavors and fragrances, but specific regulatory details are limited.
Latin America: Usage is generally aligned with international standards, but specific country regulations may vary.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

Oral Exposure: Data on acceptable daily intake (ADI) or threshold of toxicological concern (TTC) for para-methyl anisole is not clearly reported. However, it is used in flavors at low concentrations, suggesting a wide margin of safety.
Dermal Exposure: There is limited data on dermal irritation or sensitization, but it is generally considered safe for use in fragrances at typical concentrations.
Inhalation Exposure: As a volatile compound, inhalation exposure is possible, but occupational exposure limits are not well-documented. General safety practices should be followed to minimize exposure.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

para-Methyl anisole is valued for its sweet, anisic aroma, which can enhance both flavor and fragrance formulations. It synergizes well with other sweet and spicy notes, such as vanilla and cinnamon. Formulators should be cautious of its intensity, as it can easily overpower other components if used excessively. It is often under-used in complex formulations where its unique profile can add depth and character.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

The data on para-methyl anisole is well-established in terms of its sensory profile and typical uses in flavors and fragrances. However, specific regulatory and toxicological data are less documented, indicating potential gaps in comprehensive safety assessments. Industry practices often rely on historical usage and general safety standards.

Citation hooks: FlavScents

QA Check

All required sections 1–9 are present
"Citation hooks:" line is present under each section
Flavor section includes ppm ranges
Toxicology section covers oral, dermal, inhalation
Regulatory section mentions US, EU, UK, Asia, Latin America
If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-02-13 15:49:20 GMT (p2)

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CRESYL METHYL ETHER, PARA FCC • 500768

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