FlavScents AInsights Entry for Acetyl Cedrene (CAS: 80449-58-7)

1. Identity & Chemical Information

• Common Name(s): Acetyl Cedrene
• IUPAC Name: 1-(2,2,6,6-tetramethyl-1-cyclohexen-1-yl)ethanone
• CAS Number: 80449-58-7
• FEMA Number: Not available
• Other Identifiers: FL Number not available; CoE Number not available; IFRA Reference not available
• Molecular Formula: C14H22O
• Molecular Weight: 206.33 g/mol
• Functional Groups and Structure–Odor Relevance: Acetyl cedrene is a ketone with a cyclohexene ring, contributing to its woody and amber-like scent profile. The presence of the acetyl group is crucial for its odor characteristics, providing a warm, rich, and slightly sweet aroma.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

• Odor and Flavor Descriptors: Acetyl cedrene is characterized by its woody, amber, and slightly sweet scent. It is often described as having a warm and rich aroma with moderate intensity and good diffusion.
• Taste and/or Odor Thresholds: Specific thresholds are not clearly reported, but it is known for its strong impact even at low concentrations.
• Typical Sensory Role: Acetyl cedrene is primarily used as an impact note in fragrance compositions, providing depth and warmth. It can also serve as a background realism enhancer in complex scent profiles.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

• Known Natural Sources: Acetyl cedrene is not typically found in nature and is primarily synthesized for use in fragrances.
• Formation Pathways: It is synthesized through chemical processes involving the acetylation of cedrene, a sesquiterpene derived from cedarwood oil.
• Relevance to “Natural Flavor” or “Natural Fragrance” Designation: As a synthetic compound, acetyl cedrene does not qualify for natural flavor or fragrance designations.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

• Flavor Categories and Applications: Acetyl cedrene is not commonly used in flavor applications due to its primary role in fragrances.
• Functional Role in Flavor Systems: When used, it may contribute woody and amber notes to certain flavor profiles.
• Typical Use Levels: Data not found; use in flavors is rare and typically at very low concentrations.
• Stability Considerations: Acetyl cedrene is stable under normal conditions but may degrade under extreme heat or acidic conditions.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

• Fragrance Families and Product Types: Acetyl cedrene is widely used in woody, amber, and oriental fragrance families. It is found in perfumes, colognes, and personal care products.
• Functional Role: It acts as a base note, providing warmth and depth. It is often used as a modifier to enhance the richness of a fragrance.
• Typical Concentration Ranges: Typically used at concentrations ranging from 0.1% to 5% in fragrance formulations.
• Volatility and Top/Middle/Base Contribution: Acetyl cedrene is a base note with low volatility, contributing to the longevity of a fragrance.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States (FDA / FEMA GRAS): Not explicitly listed as GRAS for flavor use.
• European Union (Reg. (EC) No 1334/2008; FL Number Status): Not listed under the EU flavoring regulation.
• United Kingdom (Post-Brexit Alignment or Divergence): Follows EU regulations; no specific divergence noted.
• Asia (Japan, China, ASEAN): Limited data available; typically follows international standards.
• Latin America (e.g., Brazil, MERCOSUR): Limited data available; generally aligns with international practices.

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: Not typically relevant due to its primary use in fragrances.
• Dermal Exposure: Generally considered safe for use in personal care products at typical concentrations. IFRA guidelines should be consulted for specific restrictions.
• Inhalation Exposure: Low volatility reduces inhalation risk; however, occupational exposure should be managed with standard safety practices.
• Risk Profiles: The risk profile is more relevant to fragrance applications, with minimal concern for flavor use.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

• Why This Material is Valuable: Acetyl cedrene is valued for its ability to impart a warm, woody, and amber character to fragrances, enhancing depth and complexity.
• Typical Synergies: Pairs well with other woody and amber notes, as well as floral and oriental accords.
• Common Formulation Pitfalls: Overuse can lead to an overpowering scent; balance with other notes is crucial.
• Situations Where It is Frequently Over- or Under-Used: Often under-used in lighter fragrance compositions where its depth could be beneficial.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

• Well-Established Data: The sensory profile and fragrance applications are well-documented.
• Industry-Typical but Undocumented Practices: Use levels and specific regulatory statuses may vary; formulators should verify with current guidelines.
• Known Data Gaps or Regulatory Ambiguities: Limited data on flavor use and specific regulatory approvals in some regions.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• "Citation hooks:" line is present under each section
• Flavor section includes ppm ranges (not applicable due to limited use)
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-03-24 06:47:15 GMT (p2)