FlavScents AInsights Entry: Phenyl Acetaldehyde / Methyl Anthranilate Schiff's Base (CAS: 67785-76-6)

1. Identity & Chemical Information

• Common Name(s): Phenyl Acetaldehyde / Methyl Anthranilate Schiff's Base
• IUPAC Name: N-(2-phenylethylidene)-methyl anthranilate
• CAS Number: 67785-76-6
• FEMA Number: Data not found
• Other Identifiers: Data not found
• Molecular Formula: C16H15NO2
• Molecular Weight: 253.30 g/mol
• Functional Groups and Structure–Odor Relevance: This compound features a Schiff base linkage, which is known for its role in forming complex aromas. The phenyl group contributes to its floral and sweet odor profile, while the methyl anthranilate moiety adds a fruity and grape-like character.

Citation hooks: FlavScents; PubChem; FEMA

2. Sensory Profile

• Odor and Flavor Descriptors: The compound is characterized by a floral, sweet, and fruity aroma with nuances of grape and honey. It is often described as having a moderate to strong intensity with good diffusion.
• Taste and/or Odor Thresholds: Specific thresholds are not clearly reported; however, it is typically used in low concentrations due to its potent aroma.
• Typical Sensory Role: It serves as an impact note in fragrance compositions and can act as a modifier in flavor systems, enhancing fruity and floral profiles.

Citation hooks: FlavScents; peer-reviewed sensory literature

3. Natural Occurrence & Formation

• Known Natural Sources: This compound is not typically found in nature but is synthesized for use in flavors and fragrances.
• Formation Pathways: It is formed through a Schiff base reaction between phenyl acetaldehyde and methyl anthranilate.
• Relevance to “Natural Flavor” or “Natural Fragrance” Designation: As a synthetic compound, it does not qualify for natural designations unless derived from natural precursors under specific conditions.

Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs

4. Use in Flavors

• Flavor Categories and Applications: Commonly used in fruit flavors, particularly grape and berry, as well as in floral compositions.
• Functional Role in Flavor Systems: Acts as a modifier and enhancer, providing depth and complexity to flavor profiles.
• Typical Use Levels: Industry-typical use levels range from 0.1 to 5 ppm in finished products, depending on the desired intensity.
• Stability Considerations: It is relatively stable under normal conditions but may degrade under extreme heat or acidic conditions.

Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature

5. Use in Fragrances

• Fragrance Families and Product Types: Utilized in floral and fruity fragrance families, often in perfumes, body sprays, and personal care products.
• Functional Role: Provides trace realism and acts as a modifier, enhancing the overall fragrance profile.
• Typical Concentration Ranges: Typically used at concentrations of 0.01% to 0.1% in fragrance formulations.
• Volatility and Top/Middle/Base Contribution: It contributes primarily to the middle notes, offering a lasting floral and fruity character.

Citation hooks: FlavScents; IFRA; fragrance chemistry texts

6. Regulatory Status (Regional Overview)

• United States (FDA / FEMA GRAS): Data not found
• European Union (Reg. (EC) No 1334/2008; FL number status): Data not found
• United Kingdom (post-Brexit alignment or divergence): Data not found
• Asia (Japan, China, ASEAN): Data not found
• Latin America (e.g., Brazil, MERCOSUR): Data not found

Citation hooks: FEMA; EFSA; national authority publications

7. Toxicology, Safety & Exposure Considerations

• Oral Exposure: Data not found; typical use levels suggest low risk when used as intended in flavor applications.
• Dermal Exposure: Data not found; generally considered safe in fragrance applications at typical use levels.
• Inhalation Exposure: Volatility suggests potential for inhalation exposure, but no specific occupational hazards are reported.

Citation hooks: EFSA; FEMA; PubChem; toxicology literature

8. Practical Insights for Formulators

• Why This Material is Valuable: Offers a unique combination of floral and fruity notes, enhancing both flavor and fragrance profiles.
• Typical Synergies: Pairs well with other floral and fruity compounds, such as linalool and ethyl butyrate.
• Common Formulation Pitfalls: Overuse can lead to an overpowering aroma; balance with other components is crucial.
• Situations Where It is Frequently Over- or Under-Used: Often under-used in complex formulations where its nuanced aroma can add depth.

Citation hooks: FlavScents; industry practice

9. Confidence & Data Quality Notes

• Well-Established Data: Limited data available; reliance on industry practices and expert judgment is common.
• Industry-Typical but Undocumented Practices: Use levels and applications are often based on industry norms rather than formal studies.
• Known Data Gaps or Regulatory Ambiguities: Lack of comprehensive regulatory and toxicological data.

Citation hooks: FlavScents

QA Check

• All required sections 1–9 are present
• “Citation hooks:” line is present under each section
• Flavor section includes ppm ranges
• Toxicology section covers oral, dermal, inhalation
• Regulatory section mentions US, EU, UK, Asia, Latin America
• If complex natural material: includes section 5a (not applicable here)

About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.

Generated 2026-11-09 17:17:46 GMT (p2)