FlavScents AInsights Entry: Agastache Rugosa Callus Culture (CAS: 91770-93-3)
1. Identity & Chemical Information
- Common Name(s): Agastache rugosa callus culture
- CAS Number: 91770-93-3
- FEMA Number: Not applicable
- Other Identifiers: Not applicable
- Material Type: Natural complex material derived from plant tissue culture
- Description: Agastache rugosa callus culture is a plant-derived material obtained through tissue culture techniques. It is not a single chemical compound but a complex mixture of various constituents typical of the Agastache rugosa species.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
Agastache rugosa callus culture is known for its distinctive sensory characteristics, which include a sweet, minty aroma with subtle anise-like undertones. The intensity of the odor is moderate, providing a refreshing and uplifting scent profile. It is often used as a background realism note in both flavor and fragrance applications, contributing to the overall complexity and depth of the formulation.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
Agastache rugosa, commonly known as Korean mint, is native to East Asia and is traditionally used in herbal medicine. The callus culture is derived from the plant's tissue through in vitro techniques, allowing for the sustainable production of its aromatic compounds. This material is relevant to "natural flavor" and "natural fragrance" designations due to its plant origin and the natural processes involved in its formation.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
Agastache rugosa callus culture is utilized in flavor formulations primarily for its minty and anise-like notes. It is commonly found in confectionery, beverages, and herbal teas. Typical use levels in finished products range from 5 to 50 ppm, depending on the desired intensity and product type. The material is relatively stable under normal processing conditions but may degrade under high heat or acidic environments.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
In the fragrance industry, Agastache rugosa callus culture is valued for its fresh, minty aroma, which fits well within the aromatic and herbal fragrance families. It serves as a modifier or impact note, enhancing the freshness and complexity of the fragrance. Typical concentration ranges in formulations are from 0.1% to 1%, contributing primarily to the top and middle notes due to its moderate volatility.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
5a. Key Constituents (Typical)
- Major Constituents: Estragole, menthone, pulegone
- Note: The composition of Agastache rugosa callus culture can vary significantly based on the origin of the plant material, the specific tissue culture techniques employed, and environmental factors during cultivation.
Citation hooks: FlavScents; peer-reviewed literature; authoritative industry references
6. Regulatory Status (Regional Overview)
- United States: Not explicitly listed under FEMA GRAS; usage should comply with general safety standards.
- European Union: Not specifically listed under Regulation (EC) No 1334/2008; considered under general flavoring guidelines.
- United Kingdom: Follows EU regulations post-Brexit with no significant divergence reported.
- Asia: Limited specific regulations; generally follows international safety standards.
- Latin America: No specific listings; usage should align with general safety and regulatory practices.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
- Oral Exposure: No specific ADI or MSDI established; usage should be guided by general safety assessments and industry practices.
- Dermal Exposure: Generally considered safe in fragrance applications; no significant irritation or sensitization reported.
- Inhalation Exposure: Moderate volatility suggests low risk in typical use concentrations; occupational exposure should be monitored.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
Agastache rugosa callus culture is prized for its unique minty and anise-like profile, offering versatility in both flavor and fragrance formulations. It synergizes well with other herbal and citrus notes, enhancing freshness and complexity. Formulators should be cautious of potential degradation under extreme conditions and consider its moderate volatility when designing products.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
The data on Agastache rugosa callus culture is well-established in terms of sensory characteristics and typical applications. However, specific regulatory and toxicological data are less documented, requiring formulators to rely on general industry practices and safety assessments.
Citation hooks: FlavScents
QA Check
- All required sections 1–9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- Includes section 5a for complex natural material
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-05-18 09:09:11 GMT (p2)