FEMA | N/A |
CAS | 2447-54-3 |
EINECS | N/A |
JECFA Food Flavoring | N/A |
CoE Number | N/A |
Organoleptic Notes |
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Odor | N/A |
Flavor | N/A |
Material Notes | bactericidal produces glaucoma in laboratory animals; from argemonemexicana & sanguinaria; inhibits glutamate decarboxylase. Consumption of Sanguinarine, present in poppy seeds and in the oil of Argemone mexicana which has been used as an adulterant for mustard oil in India, has been linked to development of glaucoma. Banned by FDA Sanguinarine is a quaternary ammonium salt from the group of benzylisoquinoline alkaloids. It is extracted from some plants, including bloodroot (Sanguinaria canadensis), Mexican prickly poppy Argemone mexicana, Chelidonium majus and Macleaya cordata. It is also found in the root, stem and leaves of the opium poppy but not in the capsule.[citation needed]; Sanguinarine is a toxin that kills animal cells through its action on the Na+-K+-ATPase transmembrane protein. Epidemic dropsy is a disease that results from ingesting sanguinarine. |