| FEMA | 2097 |
| CAS | 100-66-3 |
| EINECS | 202-876-1 |
| JECFA Food Flavoring | 1241 |
| CoE Number | 2056 |
| Organoleptic Notes |
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| Odor | phenolic phenolic, gasoline, ethereal, anise, |
| Flavor | aromatic aromatic, acrylate, acetone, plastic, |
| Material Notes | Flavouring agent Anisole is a precursor to perfumes, insect pheromones, and pharmaceuticals. For example, synthetic anethole is prepared from anisole.; Anisole undergoes electrophilic aromatic substitution reaction more quickly than does benzene, which in turn reacts more quickly than nitrobenzene. The methoxy group is an ortho/para directing group, which means that electrophilic substitution preferentially occurs at these three sites. The enhanced nucleophilicity of anisole vs benzene reflects the influence of the methoxy group, which renders the ring more electron-rich. The methoxy group strongly affects the pi cloud of the ring, moreso than the inductive effect of the electronegative oxygen. |