FlavScents AInsights Entry for (±)-Camphor (CAS: 76-22-2)
1. Identity & Chemical Information
- Common Name(s): Camphor
- IUPAC Name: 1,7,7-Trimethylbicyclo[2.2.1]heptan-2-one
- CAS Number: 76-22-2
- FEMA Number: 2225
- Other Identifiers: FL No. 02.012
- Molecular Formula: C10H16O
- Molecular Weight: 152.23 g/mol
- Functional Groups and Structure–Odor Relevance: Camphor is a bicyclic monoterpene ketone. Its structure contributes to its characteristic penetrating, cooling odor, which is often described as medicinal or reminiscent of eucalyptus.
Citation hooks: FlavScents; PubChem; FEMA
2. Sensory Profile
Camphor is known for its strong, penetrating odor that is often described as medicinal, cooling, and slightly woody. It has a high intensity and is capable of diffusing quickly, making it a potent impact note in both flavor and fragrance applications. The odor threshold of camphor is relatively low, allowing it to be perceived at minimal concentrations. In sensory applications, camphor is typically used as an impact note or a modifier to add freshness and complexity.
Citation hooks: FlavScents; peer-reviewed sensory literature
3. Natural Occurrence & Formation
Camphor naturally occurs in the wood of the camphor laurel (Cinnamomum camphora), a large evergreen tree native to Asia, particularly in regions like China, Taiwan, and Japan. It can also be found in some other plants, such as rosemary and sage. Camphor is biosynthesized in plants through the mevalonate pathway, which is common for terpenoids. Its presence in natural sources qualifies it for use in "natural flavor" or "natural fragrance" designations, depending on the extraction method.
Citation hooks: FlavScents; food chemistry literature; EFSA/JECFA monographs
4. Use in Flavors
Camphor is used in flavor applications primarily for its cooling and refreshing properties. It is commonly found in minty or medicinal flavor profiles, such as those used in chewing gums, candies, and oral care products. Typical use levels in finished food or beverage products range from 1 to 20 ppm, with higher concentrations potentially leading to overpowering effects. Camphor is relatively stable under normal conditions but can degrade under high heat or acidic conditions.
Citation hooks: FlavScents; FEMA GRAS documentation; formulation literature
5. Use in Fragrances
In fragrances, camphor is utilized for its fresh, cooling, and slightly woody scent. It is often incorporated into fragrance families such as fougère, chypre, and oriental. Camphor serves as a modifier or impact note, providing a fresh top note that enhances the overall complexity of a fragrance. Typical concentration ranges in perfumes are from trace amounts up to 0.5%, depending on the desired intensity and product type.
Citation hooks: FlavScents; IFRA; fragrance chemistry texts
6. Regulatory Status (Regional Overview)
- United States: Camphor is generally recognized as safe (GRAS) for use in food by FEMA.
- European Union: Approved for use in food flavorings under Regulation (EC) No 1334/2008 with FL No. 02.012.
- United Kingdom: Follows EU regulations post-Brexit with no significant divergence reported.
- Asia: In Japan and China, camphor is permitted in food and cosmetic applications, subject to specific concentration limits.
- Latin America: Generally accepted in food and fragrance applications, with specific regulations varying by country.
Citation hooks: FEMA; EFSA; national authority publications
7. Toxicology, Safety & Exposure Considerations
Camphor is considered safe for use in food and fragrance applications at typical exposure levels. For oral exposure, the acceptable daily intake (ADI) is not explicitly defined, but usage is guided by FEMA GRAS status. Dermal exposure in fragrances is regulated by IFRA, which provides guidelines to prevent irritation and sensitization. Inhalation exposure is generally safe at typical fragrance concentrations, though occupational exposure should be monitored to avoid respiratory irritation.
Citation hooks: EFSA; FEMA; PubChem; toxicology literature
8. Practical Insights for Formulators
Camphor is valued for its ability to impart a fresh, cooling sensation in both flavors and fragrances. It synergizes well with minty and herbal notes, enhancing their freshness. Formulators should be cautious of its potency, as overuse can lead to an overpowering medicinal character. It is often under-utilized in complex fragrance compositions where subtle freshness is desired.
Citation hooks: FlavScents; industry practice
9. Confidence & Data Quality Notes
The data on camphor is well-established, with comprehensive sensory and regulatory information available. Industry practices are well-documented, though specific numeric thresholds for safety are sometimes based on typical usage rather than explicit regulatory limits. Known data gaps include precise ADI values, which are inferred from GRAS status.
Citation hooks: FlavScents
QA Check
- All required sections 1–9 are present
- "Citation hooks:" line is present under each section
- Flavor section includes ppm ranges
- Toxicology section covers oral, dermal, inhalation
- Regulatory section mentions US, EU, UK, Asia, Latin America
- If complex natural material: includes section 5a (not applicable here)
About FlavScents AInsights (Disclosure)
FlavScents AInsights integrates information from authoritative government, scientific, academic, and industry sources to provide applied, exposure-aware insight into flavor and fragrance materials. Data are drawn from regulatory bodies, expert safety panels, peer-reviewed literature, public chemical databases, and long-standing professional practice within the flavor and fragrance community. Where explicit published values exist, they are reported directly; where gaps remain, AInsights reflects widely accepted industry-typical practice derived from convergent sensory behavior, historical commercial use, regulatory non-objection, and expert consensus. All such information is clearly labeled to distinguish documented data from professional guidance or informed estimation, with the goal of offering transparent, practical, and scientifically responsible context for researchers, formulators, and regulatory specialists. This section is generated using advanced computational language modeling to synthesize and structure information from established scientific and regulatory knowledge bases, with the intent of supporting—not replacing—expert review and judgment.
Generated 2026-11-04 11:43:52 GMT (p2)